Up to five of the substitutes listed on each team's match sheet may take part in the match. Additionally, a sixth substitute listed on the match sheet may take part exclusively during extra time. A player who has been substituted may take no further part in the match. Each team may use a maximum of three stoppages in play to make substitutions (one additional stoppage in extra-time can be used). Substitutions made before the start of the match, during half-time, between the end of normal playing time and extra time, and at half-time during extra time do not reduce the number of stoppages in play that can be used.
After the match sheets have been exchanged, no changes are allowed. Before the match has kicked off, the following exceptions are possible:
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Any of the players indicated on the match sheet as forming the starting 11 who cannot start the match due to physical incapacity may be replaced by one of the substitutes listed on the match sheet. The replaced player is taken off the match sheet and the team's quota of substitute players is reduced accordingly for the match in question. During the match, five players may still be substituted.
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Any of the substitutes listed on the match sheet who cannot be fielded due to physical incapacity may not be replaced, which means that the quota of substitute players is reduced accordingly for the match in question.
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If none of the goalkeepers listed on the match sheet can be fielded due to physical incapacity, they may be replaced by registered goalkeepers not previously listed on the match sheet.
The association concerned must, upon request, provide the UEFA administration with the necessary medical certificates. Any change made to the players indicated on the match sheet as forming the starting 11 after the match sheets have been exchanged without providing due medical evidence is considered as a substitution, and the number of substitutions available to the team during the match is reduced accordingly. The replaced player may take no further part in the match.