The eight runners-up of the UEFA Champions League path group stage and the eight winners of the second round of the domestic champions path contest the play-offs. The play-off pairings are determined by means of a draw.
The play-offs are played in single-leg knockout matches in accordance with . The UEFA administration ensures that the following principles are respected:
Clubs from the same association cannot be drawn against each other.
The eight winners of the second round of the domestic champions path play at home.
The eight winners of the play-offs qualify for the round of 16.